Can Keloid Scars Cause Cancer?

Can Keloid Scars Cause Cancer
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Experts believe keloids may be linked to a gene associated with dark skin pigments. Keloids are inherited and rarely turn into fair skin. In some people, keloids can also form after minor scratches and acne. About 18 million people worldwide have a genetic predisposition to keloid formation as a result of skin trauma.

While keloids are not fatal, they can cause pain, itching, discomfort, decreased mobility, or increased self-awareness. They can also develop as a result of minor piercing injuries. They can develop after very light skin lesions, such as acne or piercings, and spread beyond the original area of ​​the skin injury. Scars that form after severe cuts or traumatic injuries, such as surgical incisions, can be enlarged or sometimes stagnant.

In rare cases, keloids form when people don’t damage their skin. Keloid scars occur as a result of the growth of scar tissue; symptoms appear at the site of previous skin damage. Keloids are raised scars that grow and extend beyond the damaged area. Unlike hypertrophic scars, keloids tend to appear outside the original injury site.

“While keloids are benign, uncontrolled growth can be a sign of skin cancer. However, if your skin is prone to keloids, anything that can cause scarring can cause keloids. Most types of skin Injury can lead to the formation of keloids. Keloids, including acne scars, burns, chickenpox scars, ear-piercing scratches, surgical incisions, vaccination sites, etc. Dark-skinned people (especially those of African, Asian or Hispanic origin) and People with red hair are more likely to develop keloids.

Keloid scars can form where the skin is damaged, such as surgical incisions, piercings, burns, chicken pox, or acne. In some cases, scar tissue can grow to form smooth, hard growths called keloids. Keloids are benign fibroproliferative tumors that cause an overgrowth of scar tissue in the skin. Although keloids are traditionally viewed as a form of skin scarring, they exhibit many cancer-like features, such as progressive uncontrolled growth, lack of spontaneous regression, and extremely high recurrence rates.

Keloids are considered benign fibroproliferative skin tumors that grow beyond the original skin lesion. Keloids are traditionally regarded as scars in a spectrum of fibroproliferative skin diseases. Despite the frequency of BCC, those that develop in scar tissue are rare, and the phenomenon of keloid BCC is rarely described in the literature.

Keloid scars can result from ear piercing, wound site infection, repeated trauma to the area, acne scarring, and spreading beyond the original area, resulting in an overgrowth of scar tissue at the site of the healed skin lesion. Skin damage. Keloid scars become larger and taller, may be pink, red, flesh-colored, or darker than the surrounding skin, and sometimes form months or even longer after the initial injury. A keloid (eg, “KEE-faithful”) is a scar that is larger and wider than the original lesion. On the chest, legs, or arms, keloids are most likely raised scars with a flat surface.

Domed or irregular shape a When a keloid mass is caused by a surgical incision or trauma, keloid scar tissue may continue to grow for some time after the wound is closed. Once a keloid stops growing, it becomes darker than human skin. If a keloid appears on the earlobe, it will most likely be round or oval. A keloid that covers a joint or a large area can reduce a person’s ability to move that part of the body.

Some people, however, have a higher risk of developing keloids when they are hacked. But treatment can be helpful if the keloid scar causes discomfort or skin mobility (for example, if it covers a joint or a large area). If you are prone to developing keloids, you should be vigilant when taking steps to prevent these scars from forming. While it is not always possible to prevent scarring injuries, the risk of scarring after an injury can be reduced.

Read also: What Causes A Keloid Scars

You can easily diagnose most scars yourself by monitoring the area of ​​skin that has healed from the injury. Scars form as part of the healing process after a cut or injury to the skin. When scar forms, collagen fibers repair damaged skin and cover open areas. Acne scars can become more visible with age because the skin loses collagen and elasticity over time.

Internal scar tissue can form as a result of surgery (such as abdominal adhesions) and certain conditions such as Asherman’s syndrome and Peyronie’s disease. An autoimmune disorder such as scleroderma causes skin changes that resemble scars due to skin inflammation. But sometimes, for reasons not yet fully understood, your skin can overreact to damage, causing scar tissue to grow that rarely goes away on its own.

Removing the keloid may mean that the scar tissue is growing back, sometimes more than before. You can prevent keloid formation by taking steps to protect your skin after it has been damaged. Keloid growth can be caused by any damage to the skin: insect bites, acne, injection, piercings, burns, hair removal, and even minor scratches and bumps. The hypertrophic scar remains within the original wound and may disappear over time without treatment.

Collagen, a protein found throughout the body, is beneficial for wound healing, but when the body produces too much of it, keloids can form. There is a potential for a key regulator or group of precursors that, when activated following skin injury, trigger a cascade of events that culminate in keloid scarring.

As previously mentioned, the link between pancreatic cancer and keloids may be related to chronic inflammation and TGF-b/Smad signaling. In short, chronic inflammation can lead to fibrosis, which can lead to the development of keloids and tumors. Numerous studies have shown that high levels of TGF-b1 in keloid tissue stimulate the proliferation and differentiation of dermal fibroblasts and the formation of collagen. In keloids, local hypoxia in the wound area accelerates wound healing by stimulating angiogenesis and inducing fibroblast proliferation, as hypoxia induces vascular endothelial growth factor (VEGF) in keloid fibroblasts expression and higher density of blood vessels in keloids than in normal dermis and scars.

Radiation therapy treatment with low-dose radiation after surgery can help prevent scarring from regrowing. The treatment softens and smoothes the skin and can improve the appearance of scars.

Read also: Is Keloid Scar Treatment Painful

When injected into a keloid, these medications help to shrink the scar. Surgery is usually combined with other treatments such as corticosteroid injections or silicone treatments; this is because keloids grow back after surgical removal in almost 100% of cases, according to the AAD. Between 90% and 100% of patients using this treatment as indicated after keloid surgery can prevent new keloid.

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